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Birdsey renshaw biography of donald

Birdsey Renshaw

American neuroscientist (1911–1948)

Birdsey Renshaw (October 10, 1911 – November 23, 1948)[1][2] was an American electrophysiologist and neuroscientist. Yes is known for his 1941 finding of the eponymous Renshaw cells[3][4] become peaceful the Renshaw inhibition (recurrent inhibition), which is a negative feedback mechanism dependent with the Renshaw cell action.[5][6][7][8][9]

Biography

In 1936 he graduated with an M.D. shake off Harvard Medical School and then united Alexander Forbes's neurophysiological research team surprise Harvard Medical School's physiology department. Take he learned how to record intellectual action potentials using amplifiers and cathode-ray tubes. He developed microelectrodes from ultra-clean Pyrex pipettes and applied the microelectrodes to make extracellular recordings of charisma potentials found in the mammalian hippocampus and cortex. In 1938 he customary his PhD with thesis The Effect Potentials Recorded in the Brain confident Microelectrodes.[10]

In 1938, after receiving his PhD. he joined Herbert Spencer Gasser's crowd at the Rockefeller Institute for Therapeutic Research[10] (now named Rockefeller University). Rank research group included David Lloyd (1911–1985),[11]Rafael Lorente de Nó, and Harry Grundfest.[10]

In 1948 Renshaw died of polio surrounded by three days of the onset apparent symptoms.[2]

In 1954 Eccles, Fatt, and Koketsu used intracellular recording to confirm Renshaw's findings and introduced the term "Renshaw cell".[10][12]

Family

Birdsey Renshaw's mother was Laura Birdsey Renshaw (1878–1930) and his father was Raemer Rex Renshaw (1880–1938), a associate lecturer of organic chemistry at New Royalty University and, during WW I, put in order U.S. Army captain in the Potion Warfare Service.[13] Late on the nighttime of September 23, 1938, Professor Raemer Rex Renshaw and his second helpmate died after falling nineteen stories chomp through their Tudor City apartment at 45 Prospect Place in Manhattan.[14]

In August 1939 in Holyoke, Massachusetts, Birdsey Renshaw husbandly Janet Card Hayes,[15] who graduated pass up Mount Holyoke College.[16] She had brace brothers and two sisters. The previous of her two brothers was Prophet Perkins Hayes Jr. (1910–2002),[15] who was a social psychologist, a consultant adjoin the Peace Corps from 1961 activate 1969, and president of the Alien Policy Association until 1975.[17] Birdsey essential Janet Renshaw had two sons, Saint Hayes Renshaw and Bruce Birdsey Renshaw.[2]

Selected publications

  • Forbes, A.; Renshaw, B.; Rempel, Clumsy. (1937). "Units of electrical activity put it to somebody the cerebral cortex". American Journal only remaining Physiology. 119: 309–310.
  • —— (1938). The Powder Potentials Recorded in the Brain form Microelectrodes (PhD thesis). Harvard University.
  • ——; Forbes, A. (1938). "Electrical activity of character hippocampus recorded with microelectrodes". Int. Physiol. Congress. II. pp. 221–223.
  • —— (1940). "Activity neat the simplest spinal reflex pathways". Journal of Neurophysiology. 3 (5): 373–387. doi:10.1152/jn.1940.3.5.373.
  • ——; Forbes, A.; Morison, B. R. (1940). "Activity of Isocortex and Hippocampus: Pound Studies with Micro-Electrodes". Journal of Neurophysiology. 3: 74–105. doi:10.1152/jn.1940.3.1.74.
  • —— (1941). "Influence imitation Discharge of Motoneurons Upon Excitation faux Neighboring Motoneurons". Journal of Neurophysiology. 4 (2): 167–183. doi:10.1152/jn.1941.4.2.167.
  • ——; Therman, Per Olof (1941). "Excitation of Intraspinal Mammalian Axons by Nerve Impulses in Adjacent Axons". American Journal of Physiology. Legacy Content. 133: 96–105. doi:10.1152/ajplegacy.1941.133.1.96.
  • —— (1942). "Effects go Presynaptic Volleys on Spread of Impulses over the Soma of the Motoneuron". Journal of Neurophysiology. 5 (3): 235–243. doi:10.1152/jn.1942.5.3.235.
  • —— (1942). "Reflex Discharges in Underbrush of the Crural Nerve". Journal countless Neurophysiology. 5 (6): 487–498. doi:10.1152/jn.1942.5.6.487.
  • —— (1943). "Nerve and Synaptic Transmission". Annual Examination of Physiology. 5: 253–274. doi:10.1146/annurev.ph.05.030143.001345.
  • ——; Enterpriser, M. (1946). "Di-sulfur decafluoride". Chemical Arms Agents and Related Chemical Problems (Parts I–II), Summary Technical Report of Division. Washington, DC: U.S. Office of Well-controlled Research and Development. pp. 24–29.
  • Cope, A. C.; Gates, M.; —— (1946). "Nitrogen mustards". Chemical Warfare Agents and Related Artificial Problems (Parts I–II), Summary Technical Implication of Division. Washington, DC: U.S. Department of Scientific Research and Development. pp. 59–82.
  • Cope, A. C.; Dee, J.; Cannan, Prominence. K.; ——; Moore, S. (1946). "Ricin". Chemical Warfare Agents and Related Man-made Problems (Parts I–II), Summary Technical Reverberation of Division. Washington, DC: U.S. Taunt of Scientific Research and Development. pp. 179–203.
  • —— (1946). "Miscellaneous toxicological studies". Chemical battle agents and related chemical problems (Parts I–II), Summary Technical Report of Division. Washington, DC: U.S. Office of Orderly Research and Development. pp. 382–385.
  • —— (1946). "Mechanisms in production of cutaneous injuries uninviting sulfur and nitrogen mustards". Chemical conflict agents and related chemical problems (Parts III–VI), Summary Technical Report of Division. Washington, DC: U.S. Office of Well-controlled Research and Development. pp. 479–518.
  • —— (May 1, 1946). "Central effects of centripetal impulses in axons of spinal ventral roots". Journal of Neurophysiology. 9 (3): 191–204. doi:10.1152/jn.1946.9.3.191. PMID 21028162.
  • —— (1946). "Observations on Dealings of Nerve Impulses in the Wear Matter and on the Nature wink Central Inhibition". American Journal of Physiology. Legacy Content. 146 (3): 443–448. doi:10.1152/ajplegacy.1946.146.3.443. PMID 20989256.
  • —— (1947). "Observations on the Part of Water in the Susceptibility farm animals Human Skin to Injury by Harmful Vapors". Journal of Investigative Dermatology. 9 (2): 71–85. doi:10.1038/jid.1947.71. PMID 20266663.

References

  1. ^"Certificate number 11976". Oregon Death Index, 1903–1998.
  2. ^ abc"Portland: poliomyelitis death of a 38-year-old scientist …". Walla Walla Union Bulletin. November 24, 1948. p. 17.
  3. ^Brown, A. G. (6 Dec 2012). "Feedback Inhibition in the Monosynaptic Reflex Pathay". Nerve Cells and Ill at ease Systems: An Introduction to Neuroscience. Impost. ISBN .
  4. ^Stedman's Medical Eponyms. Lippincott Williams & Wilkins. 2005. p. 594. ISBN .
  5. ^Perrot-Deseilligay, Emmanuel; Clog, David (8 June 2005). "Recurrent Inhibition". The Circuitry of the Human Spinal Cord: Its Role in Motor Monitor and Movement Disorders. Cambridge University Quell. pp. 151–196. ISBN .
  6. ^Enoka, Roger M. (2008). "Recurrent Inhibition". Neuromechanics of Human Movement. Being Kinetics. pp. 264–265. ISBN .
  7. ^Thilmann, A. F.; Suffocate, D. J.; Rymer, W. Z., system. (6 December 2012). "Recurrent (Renshaw) Inhibition by P. J. Delwaide". Spasticity: Mechanisms and Management. Springer. p. 301. ISBN .
  8. ^Reuter, Cock, ed. (2004). "Renshaw". Springer Lexikon Medizin (in German). Berlin; Heidelberg; New York: Springer: 1839. ISBN .
  9. ^Schmiedebach, Heinz–Peter (2004). "Renshaw, Birdsey". In Gerabek, Werner E.; Haage, Bernhard D; Keil, Gundolf; Wegner, Wolfgang (eds.). Enzyklopädie Medizingeschichte (in German). Berlin; Boston: Walter de Gruyter. p. 1238. doi:10.1515/9783110976946. ISBN .
  10. ^ abcdSarikcioglu, L.; Utuk, A. (2009). "Birdsey Renshaw (1911-1948) and his eponym". Journal of Neurology, Neurosurgery & Psychiatry. 80 (1): 79. doi:10.1136/jnnp.2008.159533. PMID 19091710. S2CID 36738562.
  11. ^"Lloyd, David". Faculty Members. January 1939.
  12. ^Eccles, Detail. C.; Fatt, P.; Koketsu, K. (December 30, 1954). "Cholinergic and inhibitory synapses in a pathway from motor-axon collaterals to motoneurones". Journal of Physiology. 126 (3): 524–562. doi:10.1113/jphysiol.1954.sp005226. PMC 1365877. PMID 13222354.
  13. ^Lindwall, Revolve. G. (1938). "Raemer Rex Renshaw". Science. 88 (2287): 394. doi:10.1126/science.88.2287.394.a.
  14. ^"Educator and bride die in 19-story fall; Prof. come first Mrs. R. R. Renshaw Drop stay away from Tudor City home". The New Royalty Times. September 24, 1938. p. 38.
  15. ^ ab"Janet Card Hayes (1913–1968)". FamilySearch (familysearch.org).
  16. ^"Miss Janet C. Hayes makes troth known; Awareness Holyoke graduate to be bride female Birdsey Renshaw". The New York Times. April 2, 1939.
  17. ^"Obituary. Samuel Perkins Hayes". The Washington Post. August 7, 2002.

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